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DHRS3 O75911

短链脱氢酶/还原酶3 (EC 1.1.1.300) (DD83.1) (视黄醛短链脱氢酶/还原酶1) (retSDR1) (视黄醇脱氢酶17) (短链脱氢酶/还原酶家族16C成员1)

蛋白质信息 (UniProt)

短链脱氢酶/还原酶3 (EC 1.1.1.300) (DD83.1) (视黄醛短链脱氢酶/还原酶1) (retSDR1) (视黄醇脱氢酶17) (短链脱氢酶/还原酶家族16C成员1)

O75911

功能描述

在NADPH存在下催化全反式视黄醛还原为全反式视黄醇。 {ECO:0000269|PubMed:9705317}。

组织特异性

Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.

亚细胞定位

Membrane

关键词

Alternative splicing Lipid metabolism Membrane NADP Oxidoreductase Proteomics identification Reference proteome Transmembrane Transmembrane helix