DERPC P0CG12

肾癌和前列腺癌蛋白表达降低

功能描述

潜在的肿瘤抑制因子。过表达时抑制前列腺肿瘤细胞生长。 {ECO:0000269|PubMed:12477976}。

组织特异性

Ubiquitously expressed, with abundant expression in kidney, skeletal muscle, testis, liver, ovary, and heart and moderate expression in prostate. Expression is significantly reduced in renal and prostate tumors. No differential expression in breast cancer cells, between lobular carcinoma and normal lobules.

亚细胞定位

Nucleus