DCLK1 O15075

丝氨酸/苏氨酸蛋白激酶DCLK1 (EC 2.7.11.1) (Doublecortin结构域包含蛋白3A) (Doublecortin样和CAM激酶样蛋白1) (Doublecortin样激酶1)

功能描述

可能的激酶，可能参与发育大脑中控制神经元迁移的钙信号通路。可能也参与成熟神经系统的功能。

组织特异性

In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain.