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CST6 Q15828

半胱氨酸蛋白酶抑制剂-M (半胱氨酸蛋白酶抑制剂-6) (半胱氨酸蛋白酶抑制剂-E)

蛋白质信息 (UniProt)

半胱氨酸蛋白酶抑制剂-M (半胱氨酸蛋白酶抑制剂-6) (半胱氨酸蛋白酶抑制剂-E)

Q15828

功能描述

组织蛋白酶L、组织蛋白酶L2(组织蛋白酶V)和天冬酰胺内肽酶的高亲和力抑制剂 (PubMed:30425301)。参与表皮角化和毛囊形态发生及维持的调节 (PubMed:30425301)。 {ECO:0000269|PubMed:30425301}。

组织特异性

Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.

亚细胞定位

Secreted.

关键词

3D-structure Disease variant Disulfide bond Ectodermal dysplasia Glycoprotein Protease inhibitor Proteomics identification Reference proteome Secreted Signal