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CSRNP1 Q96S65

半胱氨酸/丝氨酸丰富核蛋白1 (CSRNP-1) (Axin-1上调基因1蛋白) (蛋白URAX1) (TGF-β诱导凋亡蛋白3) (TAIP-3)

蛋白质信息 (UniProt)

半胱氨酸/丝氨酸丰富核蛋白1 (CSRNP-1) (Axin-1上调基因1蛋白) (蛋白URAX1) (TGF-β诱导凋亡蛋白3) (TAIP-3)

Q96S65

功能描述

结合共有序列5'-AGAGTG-3'并具有转录激活活性(By similarity)。可能具有肿瘤抑制因子功能。可能在细胞凋亡中发挥作用。{ECO:0000250, ECO:0000269|PubMed:11526492}。

组织特异性

Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues.

亚细胞定位

Nucleus

关键词

Activator Apoptosis DNA-binding Nucleus Proteomics identification Reference proteome Transcription Transcription regulation