CSAG2 Q9Y5P2

软骨肉瘤相关基因2/3蛋白 (癌/睾丸抗原24.2) (CT24.2) (紫杉醇耐药相关基因3蛋白) (TRAG-3)

功能描述

耐药相关蛋白，其表达与化疗耐药和肿瘤表型相关。也可能与恶性表型有关。

组织特异性

Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435TR and the doxorubicin-resistant multiple myelanoma lines RPMI-8226/Dox40 and RPMI-8226/MDR10V.