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COL1A1 P02452

胶原alpha-1(I)链 (I型胶原alpha-1)

蛋白质信息 (UniProt)

胶原alpha-1(I)链 (I型胶原alpha-1)

P02452

功能描述

I型胶原蛋白是I组胶原蛋白(原纤维形成胶原蛋白)的成员。

组织特异性

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

亚细胞定位

Secreted, extracellular space, extracellular matrix

关键词

3D-structure Calcium Chromosomal rearrangement Collagen Direct protein sequencing Disease variant Disulfide bond Dwarfism Ehlers-Danlos syndrome Extracellular matrix