COL16A1 Q07092

XVI型胶原α-1链

功能描述

参与介导细胞粘附并诱导整合素介导的细胞反应，例如细胞铺展和细胞形态改变。 {ECO:0000269|PubMed:16754661}。

组织特异性

In papillary dermis, is a component of specialized fibrillin-1-containing microfibrils, whereas in territorial cartilage matrix, it is localized to a discrete population of thin, weakly banded collagen fibrils in association with other collagens (at protein level). In the placenta, where it is found in the amnion, a membranous tissue lining the amniotic cavity. Within the amnion, it is found in an acellular, relatively dense layer of a complex network of reticular fibers. Also located to a fibroblast layer beneath this dense layer. Exists in tissues in association with other types of collagen.

亚细胞定位

Secreted, extracellular space, extracellular matrix