接触蛋白-5 (神经识别分子 NB-2) (hNB-2)
接触蛋白-5 (神经识别分子 NB-2) (hNB-2)
O94779功能描述
Contactins在神经系统发育期间介导细胞表面相互作用。在大脑皮层神经元中具有一些神经突生长促进活性,但在海马神经元中则没有。可能参与听觉系统中的神经元活动(通过相似性)。{ECO:0000250}。
组织特异性
Expressed in brain and kidney and at very low level in placenta. Not expressed in other tissues. In brain, it is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Expressed at moderate level in the cerebellum, substantia nigra, putamen, medulla and hippocampus. Weakly expressed in the spinal cord and caudate nucleus. Weakly or not expressed in the corpus callosum.
亚细胞定位
Cell membrane
关键词