接触蛋白-4 (脑源性免疫球蛋白超家族蛋白2) (BIG-2)
接触蛋白-4 (脑源性免疫球蛋白超家族蛋白2) (BIG-2)
Q8IWV2功能描述
Contactins在神经系统发育期间介导细胞表面相互作用。具有一定的神经突生长促进活性。可能参与突触发生。
组织特异性
Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex.
亚细胞定位
Cell membrane; Lipid-anchor, GPI-anchor. Secreted
关键词