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CLEC11A Q9Y240

C型凝集素结构域家族11成员A (C型凝集素超家族成员3) (淋巴细胞分泌C型凝集素) (骨凝集素) (干细胞生长因子) (p47)

蛋白质信息 (UniProt)

C型凝集素结构域家族11成员A (C型凝集素超家族成员3) (淋巴细胞分泌C型凝集素) (骨凝集素) (干细胞生长因子) (p47)

Q9Y240

功能描述

通过刺激间充质前体细胞分化为成熟成骨细胞来促进骨发生 (PubMed:27976999)。对成年骨骼的修复和维持很重要 (By similarity)。 {ECO:0000250|UniProtKB:O88200, ECO:0000269|PubMed:27976999}。

组织特异性

Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

亚细胞定位

Cytoplasm

关键词

Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Growth factor Lectin Osteogenesis Proteomics identification Reference proteome Secreted