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CLDN9 O95484

克劳丁-9

蛋白质信息 (UniProt)

克劳丁-9

O95484

功能描述

通过不依赖钙的细胞粘附活性,在紧密连接特异性消除细胞间隙中发挥主要作用。 {ECO:0000250|UniProtKB:O95832}.; FUNCTION: (Microbial infection) 作为丙型肝炎病毒 (HCV) 进入肝细胞的受体。 {ECO:0000269|PubMed:17804490, ECO:0000269|PubMed:20375010}.

组织特异性

Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

亚细胞定位

Cell junction, tight junction. Cell membrane

关键词

3D-structure Cell junction Cell membrane Deafness Host cell receptor for virus entry Host-virus interaction Membrane Non-syndromic deafness Proteomics identification Receptor