β-嵌合素 (β-嵌合素) (Rho GTPase激活蛋白3)
β-嵌合素 (β-嵌合素) (Rho GTPase激活蛋白3)
P52757功能描述
p21-rac的GTPase-activating protein。beta-2 chimaerin的表达不足预期会导致更高的Rac活性，因此可能在低级别肿瘤向高级别肿瘤进展的过程中发挥作用。
组织特异性
Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
亚细胞定位
Membrane
关键词