CD109 Q6YHK3

CD109抗原 (150 kDa TGF-beta-1结合蛋白) (含C3和PZP样alpha-2-巨球蛋白结构域蛋白7) (血小板特异性Gov抗原) (p180) (r150) (CD抗原CD109)

功能描述

在角质形成细胞中负向调节TGFB1信号传导。 {ECO:0000269|PubMed:16754747}。

组织特异性

Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 4 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta.

亚细胞定位

Cell membrane