CCR10 P46092

C-C趋化因子受体10型 (C-C CKR-10) (CC-CKR-10) (CCR-10) (G蛋白偶联受体2)

功能描述

趋化因子SCYA27和SCYA28的受体。随后通过增加细胞内钙离子水平转导信号，并在前B细胞系中刺激趋化作用。

组织特异性

Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.

亚细胞定位

Cell membrane; Multi-pass membrane protein.