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CCN6 O95389

细胞通信网络因子6 (CCN家族成员6) (WNT1诱导信号通路蛋白3) (WISP-3)

蛋白质信息 (UniProt)

细胞通信网络因子6 (CCN家族成员6) (WNT1诱导信号通路蛋白3) (WISP-3)

O95389

功能描述

在线粒体电子传递和线粒体呼吸中发挥作用 (PubMed:27252383)。通过其对线粒体功能的调节,可能在正常的出生后骨骼生长和软骨稳态中发挥作用 (PubMed:10471507, PubMed:27252383)。 {ECO:0000269|PubMed:10471507, ECO:0000269|PubMed:27252383}。

组织特异性

Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine (PubMed:10471507, PubMed:9843955). Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes (PubMed:10471507).

亚细胞定位

Secreted

关键词

Alternative splicing Disease variant Disulfide bond Glycoprotein Growth factor Mitochondrion Proteomics identification Reference proteome Secreted Signal