CCL26 Q9Y258

C-C基序趋化因子26 (CC趋化因子IMAC) (嗜酸粒细胞趋化因子-3) (巨噬细胞炎性蛋白4-alpha) (MIP-4-alpha) (小诱导细胞因子A26) (胸腺基质趋化因子-1) (TSC-1)

蛋白质信息 (UniProt)

C-C基序趋化因子26 (CC趋化因子IMAC) (嗜酸粒细胞趋化因子-3) (巨噬细胞炎性蛋白4-alpha) (MIP-4-alpha) (小诱导细胞因子A26) (胸腺基质趋化因子-1) (TSC-1)

Q9Y258

功能描述

嗜酸性粒细胞和嗜碱性粒细胞的趋化因子 (PubMed:10415065, PubMed:10488147)。作为C-C chemokine receptor CCR3的配体，触发嗜酸性粒细胞内的Ca(2+)动员 (PubMed:10415065, PubMed:10488147, PubMed:11425309)。亦作为CX3C chemokine receptor CX3CR1的配体，诱导细胞趋化 (PubMed:20974991)。 {ECO:0000269|PubMed:10415065, ECO:0000269|PubMed:10488147, ECO:0000269|PubMed:11425309, ECO:0000269|PubMed:20974991}。

组织特异性

Ubiquitously expressed at low levels in various tissues including heart and ovary.

亚细胞定位

Secreted

关键词

3D-structure Chemotaxis Cytokine Direct protein sequencing Disulfide bond Inflammatory response Proteomics identification Reference proteome Secreted Signal

外部链接

UniProt: Q9Y258

NCBI Gene

GeneCards