含卷曲螺旋结构域蛋白3 (Fat/vessel-derived secretory protein) (Favine)
含卷曲螺旋结构域蛋白3 (Fat/vessel-derived secretory protein) (Favine)
Q9BQI4功能描述
通过抑制ECs中TNF诱导的NF-kappaB激活，负向调节内皮细胞(ECs)中TNF诱导的促炎反应 (PubMed:25193116)。正向调节脂肪细胞中的脂质积聚 (By similarity)。 {ECO:0000250|UniProtKB:Q9D6Y1, ECO:0000269|PubMed:25193116}。
组织特异性
Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC).
亚细胞定位
Secreted
关键词