CC2D2A Q9P2K1

含卷曲螺旋和C2结构域蛋白2A

功能描述

Tectonic-like复合体的组分，该复合体定位于初级纤毛的过渡区，作为屏障防止跨膜蛋白在纤毛膜和质膜之间扩散。为纤毛发生和音猬因子/SHH信号传导所必需（通过相似性）。{ECO:0000250, ECO:0000269|PubMed:18513680}。

组织特异性

Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart.

亚细胞定位

Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.