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CALY Q9NYX4

神经元特异性囊泡蛋白calcyon

蛋白质信息 (UniProt)

神经元特异性囊泡蛋白calcyon

Q9NYX4

功能描述

与clathrin轻链A相互作用,并促进clathrin自组装和clathrin介导的内吞作用。 {ECO:0000269|PubMed:16595675}。

组织特异性

Expressed in the pyramidal cells of the prefrontal cortex, in hypothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.

亚细胞定位

Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.

关键词

Alternative splicing Cell membrane Cytoplasmic vesicle Endocytosis Glycoprotein Membrane Proteomics identification Reference proteome Transmembrane Transmembrane helix