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CALU O43852

钙网蛋白 (Crocalbin) (IEF SSP 9302)

蛋白质信息 (UniProt)

钙网蛋白 (Crocalbin) (IEF SSP 9302)

O43852

功能描述

参与调节维生素K依赖性的多个N末端谷氨酸残基的羧化。似乎抑制γ-羧化酶GGCX。以低亲和力结合7个钙离子(通过相似性)。{ECO:0000250}。

组织特异性

Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.

亚细胞定位

Endoplasmic reticulum membrane

关键词

Acetylation Alternative splicing Calcium Direct protein sequencing Endoplasmic reticulum Glycoprotein Golgi apparatus Membrane Metal-binding Phosphoprotein