CACUL1 Q86Y37

CDK2相关含cullin结构域蛋白1 (Cdk相关cullin 1)

功能描述

细胞周期相关蛋白，能够通过在G1/S期转换时激活CDK2促进细胞增殖。 {ECO:0000269|PubMed:19829063}。

组织特异性

Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase.