电压依赖性L型钙通道亚基β-1 (CAB1) (钙通道电压依赖性亚基β 1)
电压依赖性L型钙通道亚基β-1 (CAB1) (钙通道电压依赖性亚基β 1)
Q02641功能描述
L-type calcium channels的调节亚基 (PubMed:1309651, PubMed:15615847, PubMed:8107964)。调节以CACNA1A为成孔亚基的L-type calcium channels的活性 (By similarity)。调节以CACNA1C为成孔亚基的L-type calcium channels的活性，并增加通道复合物在细胞膜上的存在 (PubMed:15615847)。以CACNA1D为成孔亚基的L-type calcium channels的功能表达所必需 (PubMed:1309651)。调节以CACNA1B为成孔亚基的L-type calcium channels的活性 (PubMed:8107964)。 {ECO:0000250|UniProtKB:P19517, ECO:0000269|PubMed:1309651, ECO:0000269|PubMed:15615847, ECO:0000269|PubMed:8107964}。
组织特异性
Detected in heart ventricle (at protein level) (PubMed:15615847). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
亚细胞定位
Cell membrane, sarcolemma
关键词