BTC P35070

Probetacellulin [切割产生：Betacellulin (BTC)]

蛋白质信息 (UniProt)

Probetacellulin [切割产生：Betacellulin (BTC)]

P35070

功能描述

结合EGFR、ERBB4及其他EGF受体家族成员的生长因子。视网膜色素上皮细胞和血管平滑肌细胞的有效有丝分裂原。 {ECO:0000269|PubMed:8570211}。

组织特异性

Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.

亚细胞定位

[Betacellulin]: Secreted, extracellular space.; SUBCELLULAR LOCATION: [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.

关键词

3D-structure Cell membrane Disulfide bond EGF-like domain Glycoprotein Growth factor Membrane Mitogen Proteomics identification Reference proteome

UniProt: P35070

NCBI Gene

GeneCards