ADP-核糖基环化酶/环ADP-核糖水解酶2 (EC 3.2.2.6) (ADP-核糖基环化酶2) (骨髓基质细胞抗原1) (BST-1) (环ADP-核糖水解酶2) (cADPR水解酶2) (CD抗原CD157)
ADP-核糖基环化酶/环ADP-核糖水解酶2 (EC 3.2.2.6) (ADP-核糖基环化酶2) (骨髓基质细胞抗原1) (BST-1) (环ADP-核糖水解酶2) (cADPR水解酶2) (CD抗原CD157)
Q10588功能描述
催化NAD(+)合成环ADP-beta-D-核糖(cADPR)，并将其水解为ADP-D-核糖(ADPR) (PubMed:7805847)。已知环ADPR作为内源性第二信使，引起钙离子从胞内库释放，从而调节胞内钙离子的动员 (Probable)。可能参与前B细胞生长 (Probable)。 {ECO:0000269|PubMed:7805847, ECO:0000305|PubMed:11866528, ECO:0000305|PubMed:7805847, ECO:0000305|PubMed:8202488}。
组织特异性
Expressed in various tissues including placenta, lung, liver and kidney.
亚细胞定位
Cell membrane; Lipid-anchor, GPI-anchor
关键词