BRINP3 Q76B58

BMP/视黄酸诱导型神经特异性蛋白3 (DBCCR1样蛋白1)

功能描述

通过负调控细胞周期转换抑制神经元细胞增殖。过表达时，促进垂体促性腺细胞增殖、迁移和侵袭。可能在垂体肿瘤发生中发挥作用。 {ECO:0000269|PubMed:17138656}。

组织特异性

Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.

亚细胞定位

Secreted