BCL9L Q86UU0

B细胞CLL/淋巴瘤9样蛋白 (B细胞淋巴瘤9样蛋白) (BCL9样蛋白) (蛋白BCL9-2)

功能描述

作为激活因子的转录调节因子。促进β-连环蛋白的转录活性。在肿瘤发生中起作用。增强CTNNB1的肿瘤转化活性（通过相似性）。{ECO:0000250}。

组织特异性

Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.

亚细胞定位

Nucleus