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ASB10 Q8WXI3

锚蛋白重复和SOCS盒蛋白10 (ASB-10)

蛋白质信息 (UniProt)

锚蛋白重复和SOCS盒蛋白10 (ASB-10)

Q8WXI3

功能描述

可能是SCF样ECS (Elongin-Cullin-SOCS-box protein) E3泛素-蛋白连接酶复合物的底物识别组分,该复合物介导靶蛋白的泛素化及其随后的蛋白酶体降解。 {ECO:0000250}。

组织特异性

Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve; slightly lower levels in the ciliary body, retina, and choroid; and very low levels in the lens.

亚细胞定位

Cytoplasm

关键词

Alternative splicing ANK repeat Cytoplasm Disease variant Glaucoma Nucleus Proteomics identification Reference proteome Repeat Ubl conjugation pathway