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ARHGAP8 P85298

Rho GTPase激活蛋白8 (Rho型GTPase激活蛋白8)

蛋白质信息 (UniProt)

Rho GTPase激活蛋白8 (Rho型GTPase激活蛋白8)

P85298

功能描述

Rho型GTPases的GTPase激活蛋白,通过将其转化为非活性的GDP结合状态。 {ECO:0000250}。

组织特异性

Highly expressed in kidney and placenta. Also expressed in colon, skeletal muscle, small intestine, stomach, and testis. Not detected in brain, liver or spleen. Overexpressed in the majority of colorectal tumors examined.

关键词

Alternative splicing GTPase activation Proteomics identification Reference proteome