2型血管紧张素II受体 (血管紧张素II 2型受体) (AT2受体)
2型血管紧张素II受体 (血管紧张素II 2型受体) (AT2受体)
P50052功能描述
血管紧张素II（一种血管收缩肽）的受体 (PubMed:28379944, PubMed:29967536, PubMed:31899086, PubMed:8185599)。主要通过非经典的非G蛋白和非β-抑制蛋白依赖途径进行信号转导 (PubMed:28379944)。与MTUS1协作抑制ERK2激活和细胞增殖 (PubMed:15123706)。 {ECO:0000269|PubMed:15123706, ECO:0000269|PubMed:28379944, ECO:0000269|PubMed:29967536, ECO:0000269|PubMed:31899086, ECO:0000269|PubMed:8185599}。
组织特异性
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.
亚细胞定位
Cell membrane
关键词