ADA2 Q9NZK5

腺苷脱氨酶2 (EC 3.5.4.4) (猫眼综合征关键区蛋白1)

功能描述

腺苷脱氨酶，可能促进细胞外腺苷的降解，腺苷是一种控制多种细胞反应的信号分子。需要较高的腺苷水平才能达到最佳酶活性。通过蛋白聚糖结合到细胞表面，可能在不依赖其酶活性的情况下参与细胞增殖和分化的调节。 {ECO:0000269|PubMed:20147294, ECO:0000269|PubMed:20453107}。

组织特异性

Detected in blood plasma (at protein level). Widely expressed, with most abundant expression in human adult heart, lung, lymphoblasts, and placenta as well as fetal lung, liver, and kidney. In embryo, expressed in the outflow tract and atrium of the developing heart, the VII/VIII cranial nerve ganglion, and the notochord.

亚细胞定位

Secreted