ACP4 Q9BZG2

睾丸酸性磷酸酶 (EC 3.1.3.2) (酸性磷酸酶4)

功能描述

可能去磷酸化受体酪氨酸蛋白激酶ERBB4并抑制其配体诱导的蛋白水解切割 (PubMed:15219672)。可能在牙齿发生中发挥作用 (PubMed:27843125)。 {ECO:0000269|PubMed:15219672, ECO:0000269|PubMed:27843125}。

组织特异性

Expressed mainly in the testis. Also expressed in the brain where they are enriched at the postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle. Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is expressed in the testis, trachea, prostate and bone marrow.

亚细胞定位

Membrane