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ACOT13 Q9NPJ3

酰基辅酶A硫酯酶13 (酰基辅酶A硫酯酶13) (EC 3.1.2.-) (Hotdog折叠硫酯超家族成员2) (棕榈酰辅酶A水解酶) (EC 3.1.2.2) (硫酯超家族成员2) (THEM2) [切割为：酰基辅酶A硫酯酶13，N端加工]

蛋白质信息 (UniProt)

酰基辅酶A硫酯酶13 (酰基辅酶A硫酯酶13) (EC 3.1.2.-) (Hotdog折叠硫酯超家族成员2) (棕榈酰辅酶A水解酶) (EC 3.1.2.2) (硫酯超家族成员2) (THEM2) [切割为：酰基辅酶A硫酯酶13，N端加工]

Q9NPJ3

功能描述

催化acyl-CoAs水解为游离脂肪酸和辅酶A (CoASH)，调节它们各自的细胞内水平 (PubMed:16934754, PubMed:19170545)。对中链(C12)和长链(C18)脂肪酰CoA底物具有酰基硫酯酶活性 (By similarity) (PubMed:16934754, PubMed:19170545)。也能水解3-羟苯乙酰CoA和3,4-二羟苯乙酰CoA (体外) (By similarity) (PubMed:16934754, PubMed:19170545)。可能在控制适应性产热中发挥作用 (By similarity)。 {ECO:0000250|UniProtKB:Q9CQR4, ECO:0000269|PubMed:16934754, ECO:0000269|PubMed:19170545}。

亚细胞定位

Cytoplasm, cytosol

关键词

3D-structure Acetylation Alternative splicing Cytoplasm Cytoskeleton Hydrolase Lipid metabolism Metal-binding Mitochondrion Nucleus

外部链接

UniProt: Q9NPJ3
NCBI Gene